Researchers show insulin production could be restored by boosting immune system

Researchers show insulin production could be restored by boosting immune system

The universities of Yale and California researchers have shown that insulin production could be restored by boosting the immune system. The target of Treg intervention is to prevent the progression and development of type-1 diabetes. It is aiming at freeing people from the everyday grind of insulin therapy and lifetime fear of problems.

The researchers know from more than 10 years that in a normal functioning pancreas, billions of ‘T-regs’ work as ‘peacekeepers’ for the protection of insulin-making cells from the attack of the body’s immune system.

In the latest treatment, things known as T-regulatory immune cells-or Tregs have been used. They can slow down the attack of the immune system on beta cells while still letting it to carrying on battling infections. The treatment has thus countered the requirement for regular injections of the hormone.

A professor in Metabolism and Endocrinology at the University of California, Dr. Jeffrey Bluestone, said this may prove a game-changer. After placing those Tregs into a growth medium for boosting their numbers by 1,500%, they were put back into the patient’s body.

In America, nearly 29.1 million people, or 9.3% of the population, have diabetes. Dr. Jeffrey Bluestone added, “We may be able to really change the course of this disease”.

In the study trial, improvement in glucose control and insulin secretion was seen in people, having both type 1 and type 2 diabetes.

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