Virus could be the reason for inflammatory bowel disease
The higher instances of inflammatory bowel diseases have been linked to diversity of virus present in the digestive systems of individuals, according to researchers at Washington University School of Medicine in St Louis. The detailed results of the study have been published in journal Cell.
The research team in Washington suggests that in majority of individuals suffering from inflammatory bowel disease, the variety of virus found in the digestive system was higher compared to healthy individuals. The researchers pointed out that the role of the microbiome in various illnesses can’t be denied.
The research team analyzed the data for three sets of patients suffering from Crohn's disease or ulcerative colitis, living in Boston, Chicago and the United Kingdom.
The change in gut microbiome has been earlier linked to metabolism issues, obesity and diabetes. Inflammatory bowel diseases could also be caused by the change in the virus found in the digestive system. Changes in the gut that eliminate bacteria in inflammatory bowel diseases may unleash bacteriophages in the dying bacteria.
Study lead author Herbert W Virgin said, "This is the tip of the iceberg. A significant portion of the viral DNA we identified in these patients is unfamiliar to us - it comes from newly identified viruses we don't know much about."
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